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Optimization of Reflux Extraction Process of Radix Scutellariae by Central Composite Design/Response Surface Method / 中国中医药信息杂志
Chinese Journal of Information on Traditional Chinese Medicine ; (12)2008.
Artigo em Chinês | WPRIM | ID: wpr-579608
ABSTRACT
Objective To obtain the optimal extraction process of Prunella vulgaris L.Methods With the dependent variables of ethanol concentration,reflux time and solvent fold,and dependent variable of the amount of baicalin,Central Composite Design/Response Surface Method was applied to optimize the reflux extraction process.Predictions were carried out by comparing the observed and predicted values.Results The optimum conditions of extraction process were 45% ethanol,2 hours for reflux,4 fold sovent.Regression coefficients of binomial fitting complex model was 0.9759.Bias between observed values and predicted values was-3.86%.Conclusion The optimum model is simple,precise and highly predictive.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Information on Traditional Chinese Medicine Ano de publicação: 2008 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Information on Traditional Chinese Medicine Ano de publicação: 2008 Tipo de documento: Artigo