Experimental study on regulation of lipid metabolism by extract of Ocimum basilicum L. in rat with hyperlipidemia / 中成药

ABSTRACT

AIM:To explore the effects of extract from Ocimum basilicum L.(OBL)on regulation of lipid metabolism in rat with hyperlipidemia.METHODS:Rat model was eatablished by being douched high fat emulsion and blood samples were collected in 28 days,the total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),the liver slurry of TC、TG and the index of liver were measured.RESULTS:Two extracts of OBL diminished the serum concentration of TC and LDL and TC and TG in the liver slurry,and increased the HDL level.CONCLUSION:The extract of OBL could regulate the lipid metabolism,prevent and treat hyperlipidemia.