Simultaneous determination of serum tauro-conjugated bile acids in intrahepatic cholestasis of pregnancy patients by high performance liquid chromatography-tendem mass spectrometry / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-579778
ABSTRACT
Objective:
To investigate the individual serum tauro-conjugated bile acid concentration in patients with Intrahepatic Cholestasis of Pregnancy(ICP) by high performance liquid chromatography-tendem mass spectro-metry(HPLC-MS/MS).Methods:
Bile acids were extracted from serum samples of ICP,ICP with Diabetes Mellitus,ICP with Virus Hepatitis patients and normal pregnant women.Serum tauro-conjugated bile acids were measured by HPLC-MS/MS.Results:
The serum levels of taurocholic acid(TCA),taurochenode-oxycholic acid(TCDCA) and taurodeoxycholic acid(TDCA) in the three groups of ICP,ICP with Diabetes Mellitus,and ICP with Virus Hepatitis were significantly higher than those of the control group(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Chongqing Medical University
Ano de publicação:
2003
Tipo de documento:
Artigo
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