Apparent partition coefficient of Hawthorn leaf flavonoids in phospholipids complex / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Article
em Zh
| WPRIM
| ID: wpr-579865
Biblioteca responsável:
WPRO
ABSTRACT
AIM: To explore the appearent partition coefficient of flavonoids from Hawthorn leaf in phospholids complex. METHODS: With the aid of the shake-flask method,The contents of rhamnosylvitexin,rutin and quercetin were determined by HPLC and apparent partition coefficient in the system of n-octyl alcohol and water of each ingredient in the physical mixture of Hawthorn leaf flavonoids and phospholipids,Hawthorn leaf flavonoids and its phospholipids complex were calculated respectively. RESULTS: Apparent partition coefficient of rhamnosylvitexin and rutin and quercetin in phospholipids complex were enhanced comparing with both in Hawthorn leaf flavonoids and the physical mixture of Hawthorn leaf flavonoids and phospholipids. CONCLUSION: Phospholipid complex may be an effective carrier to elevate the oral bioavailability of total flavonoids from effective fraction of Hawthorn leaf.
Texto completo:
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Traditional Patent Medicine
Ano de publicação:
1992
Tipo de documento:
Article