Elastase-induced intracranial aneurysm by means of endovascular balloon occlusion:preparation of animal model and progress in its applications / 介入放射学杂志

ABSTRACT

It is of capital importance to establish a reliable experimental animal model of intracranial aneurysm which should be extremely similar to human intracranial aneurysm in histological and hemodynamic aspects.For recent years,the elastase-induced aneurysm model by means of endovascular balloon occlusion has been widely used abroad.This paper aims to review the preparation of animal mode,the advantages and disadvantages of such a model as well as the recent progress in its applications.