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Antiproliferation of human colon carcinoma cell line (SW480) by Compound Changtai Granule / 中成药
Chinese Traditional Patent Medicine ; (12)1992.
Artigo em Chinês | WPRIM | ID: wpr-580710
ABSTRACT

AIM:

To check the antiproliferative and apoptosis-inducing effect of Compound Changtai Granule(Radix et Rhizoma ginseng,Semen coicis,Rhizoma curcumae,etc)(CCG) on human colon carcinoma cell line(SW480).

METHODS:

Methy thiazolyl tetrazolium chromatomerry was used to observe the influence of several concentration of CCG on SW480 cell proliferation cultured in vitro at the various times,and flow cytometry was applied to examining the change in SW480 cell proliferation cycle and apoptosis rate.

RESULTS:

CCG could successfully prevent SW480 cell from entering G0/G1 phase and G2/M phase,decrease cell numbers in S phase at the same time.

CONCLUSION:

CCG has an obvious dose-response relationship in the range of 3.51 to 7.81 mg/mL.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Traditional Patent Medicine Ano de publicação: 1992 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Traditional Patent Medicine Ano de publicação: 1992 Tipo de documento: Artigo