Magnetic resonance imaging of spinal cord in acute transverse myelitis,neuromyelitis optica and multiple sclerosis / 重庆医科大学学报

ABSTRACT

Objective:To investigate the magnetic resonance imaging(MRI) findings of spinal cord between neuromyelitis optica(NMO),and multiple sclerosis(MS).Methods:Subjects who were diagnosed or suspected as NMO or MS in the hospital since 2004 underwent free MRI(1.5T)scanning and imaging analysis of the brain,spinal cord and eye free.with reference to magnetic records,the results of cerebrospinal fluid(CSF)and visual evoked potential(VEP),patients who fulfilled the diagnostic criteria for the latest diagnostic criteria for NMO or McDonald Criteria for MS were enrolled and the follow-up study were carried out.Results:41 patients with NMO and 121patients with MS were included in this study.As to spinal cord injury,In NMO,most patients’number of affected segments was more than 5(78.1%),and most of the patients suffered either cervical spinal cord injury or cervical-thoracic spinal cord joint injury(80.5%).The lesions changed continually,and the spinal cord swelled obviously in acute phase,with white and gray matter of spinal cord injured simultaneously.For most MS patients,the thoracic spinal injury was frequent(46.6%).There were 41 patients(59.4%)whose affected segments were more than 3,but the affection was discontinuous and progressive,and the majority was white matter injury.There was statistical difference in the affected segments between the two groups(P