Prevalence and Specificity of Unexpected Antibody Using Antibody Screening Test Including Dia and Mia Cells / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 340-346, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-58245
ABSTRACT
BACKGROUND:
The purpose of this study was to examine the prevalence and distribution of unexpected antibodies detected in the Korean population with race-specific RBC panel cells. In spite of a relatively high prevalence of Dia and Mia antigen phenotype in the Korean and Southeast Asian population, there has been little documented research on the prevalence and clinical significance of anti-Dia and anti-Mia in Korea.METHODS:
We analyzed the results of 17, 664 antibody screening tests performed during the recent 30-month period from March 2001 to September 2003. Antibodies were screened and identified by using LISS/Coombs gel card with DiaMed-ID system (DiaMed AG, Cressier, Morat, Switzerland) including Dia and Mia panel cells.RESULTS:
The prevalence of unexpected antibodies was 1.2% (214/17, 664); antibodies detected most frequently were anti-Rh (74 patients), followed by anti-Lewis (21 patients) and anti-Dia (15 patients). Out of 6, 345 patients, anti-Mia was detected in three patients (0.047%). Anti-Dia and anti-Mia had the specificity of IgG. Anti-Dia was thought as an immune-mediated antibody, whereas anti-Mia was considered as a mixed type with immune and natural antibodies.CONCLUSIONS:
This study shows that anti-Dia and anti-Mia antibodies are detected frequently in the Korean population; hence, it seems that Dia and Mia panel cells should be incorporated into antibody screening panels in Korea for safe transfusion.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Imunoglobulina G
/
Programas de Rastreamento
/
Prevalência
/
Sensibilidade e Especificidade
/
Povo Asiático
/
Coreia (Geográfico)
/
Anticorpos
Tipo de estudo:
Estudo diagnóstico
/
Estudo de prevalência
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo
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