Experimental study on efficacy of perichondrium and an acellular cartilage matrix for generating cartilage / 中国微创外科杂志

ABSTRACT

Objective To study the possibility of generating cartilage with a free composite graft of perichondrium and matrix. Methods A composite graft of a free perichondrium flap wrapped around acellular auricular cartilage matrix was implanted in the back subcutaneously of young New Zealand rabbits (GroupⅠ). As controls,double folded perichondrium free flap (GroupⅡa) and acellular auricular cartilage matrix without perichondrium cover (GroupⅡb) were implanted. Results 3 weeks and 6 weeks after implantation , obvious differences of chondroblasts derived from the perichondrium were observed between the GroupⅠand GroupⅡa (P