Correlative study between mutation in plasma platelet-activating factor acetylhydrolase gene mutation(Val279-Phe) and cerebral vascular disease / 临床神经病学杂志
Journal of Clinical Neurology
;
(6)1997.
Artigo
em Chinês
| WPRIM
| ID: wpr-582839
ABSTRACT
Objective To study the correlation between the mutation in platelet activating factor (PAF) acetylhydrolase gene mutation(Val279 Phe)and cerebral vascular disease (CVD)in Chinese.Methods Genomic DNA was analysed for the mutation allele in 153 patients with cerebral vascular disease and 100 healthy subjects matched for age and sex without CVD by a specific polymerase-chain reaction. Plasma PAF acetylhydrolase activity was determined by the method of Stafforini et al.Results The prevalence of the mutation and the frequency of the mutation allele are significantly higher in patient with CVD than those in control subjects( P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Clinical Neurology
Ano de publicação:
1997
Tipo de documento:
Artigo
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