Statistical analysis of serum lipid classification and phenotyping of Beijing professional populations / 中华检验医学杂志

ABSTRACT

Objective To study the characteristics of lipid level classification and phenotyping of Beijing professional populations. Method 4 033 cases (M/F=2 835/1 198, aged 40～91) were enrolled in the study. Lipid levels were classified according to the "Recommended guidelines for prevention and treatment of dyslipidemia" of China (1997) and NCEP ATPⅢ(2001) of US. Results High prevalence of lipid abnormality was found in Beijing populations, only 1/3 cases had desirable cholesterol (TC) and triglyceride (TG) level in the groups with age above 50, and more than half of the subjects had high TC levels at this age, the occurrence of high TG was much less than high TC. Hyperlipoproteinemia typeⅡa was 2～3 times more than type Ⅳ.Decreased high density lipoprotein cholesterol (HDL-C) was found in 20% male subjects, but only 5% in females. The prevalence of high level HDL-C was found in 25%～39% of female groups, and 10%～14% in male groups. High HDL-C was usually associated in cases with high TC, but low HDL-C was usually seen in high TG cases.Conclusion The results showed that the prevalence of lipid abnormality was as high as 2/3 of the studied subjects above age 50, it means that the cardiovascular disease risk is high in this population, Lipid modification may be beneficial to primary prevention of coronary artery disease.