Effect of 0.05% Cyclosporine A on the Ocular Surface after Photorefractive Keratectomy
Journal of the Korean Ophthalmological Society
; : 710-717, 2016.
Article
em Ko
| WPRIM
| ID: wpr-58330
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To evaluate the effect of 0.05% cyclosporine A on the ocular surface after photorefractive keratectomy (PRK). METHODS: This retrospective study included 50 patients who underwent PRK. Patients were divided into two groups: 25 patients in group I were treated with topical 0.05% cyclosporine A with conventional medication, and 25 patients in group II were treated with conventional medication. Visual acuity (VA), tear break-up time (BUT), fluorescein staining score (F-stain), Schirmer I test, and ocular surface disease index (OSDI) were evaluated before surgery and 2 weeks, 1 month, 2 months, and 3 months after surgery. RESULTS: F-stain was significantly lower in group I than in group II at 2 weeks and 1 month (p < 0.05). There was no significant difference in uncorrected VA, BUT, Schirmer I test, or OSDI between the groups. However, group I showed a more effective pattern in dry eye. CONCLUSIONS: Combination treatment with 0.05% cyclosporine A was helpful for early ocular surface stability in patients with dry eye after PRK.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Lágrimas
/
Acuidade Visual
/
Estudos Retrospectivos
/
Ciclosporina
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Ceratectomia Fotorrefrativa
/
Fluoresceína
/
Procedimentos Cirúrgicos Refrativos
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
2016
Tipo de documento:
Article