Restoration of endothelial function after reperfusio injury by tetrahydrobiopterin / 中国介入心脏病学杂志
Chinese Journal of Interventional Cardiology
;
(4)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-583362
ABSTRACT
Objective To evaluate the influence of tetrahydrobiopterin on NO and MDA concentration and SOD activity as well as the myocardial infarction area. Methods Twenty-four rabbits were divided into three groups randomly control group,MI/R group and BH 4 group. After occlusion of the left anterior descending coronary artery of a rabbit for 60 minutes followed by 90 minutes of reperfusion (ischemia/reperfusion),NO and MDA and SOD concentrations were measured and the myocardial infarction area was caculated. Results Compared with control group,the NO concentration in MI/R group was markedly decreased [(28?10) ?mol/L vs (116?17) ?mol/L,P 0.05];There was significant difference between MI/R and BH 4 groups in infarction area,too. [(18?4)% vs (16?4)%,P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Interventional Cardiology
Ano de publicação:
2003
Tipo de documento:
Artigo
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