An association analysis of apolipoprotein E genotype and Alzheimer's disease in old population in Urumqi / 临床神经病学杂志
Journal of Clinical Neurology
; (6)1995.
Article
em Zh
| WPRIM
| ID: wpr-584018
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WPRO
ABSTRACT
Objective To analyse the correlation of apolipoprotein E genotype and Alzheimer's disease(AD) in old population in Urumqi.Methods The polymerase chain reaction and restriction fragment length polymorphism(PCR-RFLP) techniques were used to detect the distribution of genotype, gene frequency of ApoE alleles in 60 cases with sporadic AD and 90 normals as control.Results The frequency of ApoE?2, ApoE?3, ApoE?4 was 6.67%, 75.83% and 17.50% respectively in AD group, while in control group, it was 13.33%, 79.45% and 7.22% respectively. The frequency of ApoE?4 allele in AD group was higher than that in control group( P
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WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Neurology
Ano de publicação:
1995
Tipo de documento:
Article