The effects of hyperthermia on apoptosis in human colonic carcinoma cell line Lovo / 医学研究生学报
Journal of Medical Postgraduates
;
(12)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-584792
ABSTRACT
Objective:
To study the effects of hyperthermia on apoptosis in human colonic cacinoma cell line Lovo.Methods:
Lovo cells were exposed to hyperthemia and apoptosis was measured with fluorescent Hocehst 33258 staining, electropherogram gel, flow cytometry (FCM).Results:
Significant changes in cell morphology , apoptosis peak apeared before the G1 phase and DNA ladder was observed in various group cells which were exposed to different temperature and in different time. Most significent changes were observed in cells exposed to 43℃ for 3,4 h and 44℃ for 1,2 h. Also cell cycle was found changed.Conclusion:
Hyperthermia can cause apoptosis in human colonic cacinoma cell line Lovo, and has phase-specificity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Medical Postgraduates
Ano de publicação:
2003
Tipo de documento:
Artigo
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