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Studies on relationship between resistance to vancomycin and changes of coagulase gene sequences of S.aureus / 临床检验杂志
Chinese Journal of Clinical Laboratory Science ; (12)2006.
Artigo em Chinês | WPRIM | ID: wpr-586123
ABSTRACT
Objective To induce vancomycin-resistantant S.aureus in vitro and to observe the changes of coagulase gene sequences of S.aureus and its relationship with vancomycin resistance.Methods DNA sequences of the coagulase were examined by polymerase chain reaction-sigle strand conformation polymorphism(PCR-SSCP) method and were identified by sequencing.Results The altered DNA sequence of coagulase in 1 strain of S.aureus was found.Conclusion The variation of DNA sequences of coagulase gene is probably linked to vancomycin-resistance in S.aureus.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Laboratory Science Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Clinical Laboratory Science Ano de publicação: 2006 Tipo de documento: Artigo