In vitro protection of Jurkat cells from daunorubicin induced apoptosis by normal bone marrow stromal cells / 中国输血杂志
Chinese Journal of Blood Transfusion
;
(12)1988.
Artigo
em Chinês
| WPRIM
| ID: wpr-586379
ABSTRACT
Objective To study the influence of bone marrow microenvironment on leukemic cells during chemotherapy and the influence on leukemic cells' drug-resistance and anti-apoptosis. Methods Normal bone marrow stromal cells were isolated using Percoll, and then were cocultured with human acute lymphocyte leukemic cell line Jurkat cells in vitro. Apoptosis percentage of Jurkat cells labelled with Annexin V/PI were detected by FCM. Results Apoptosis percentage of Jurkat cells cocultured with bone marrow stromal cells for 24 hours was lower than those maintained in suspension (P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Blood Transfusion
Ano de publicação:
1988
Tipo de documento:
Artigo
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