Serum IL-18 Level in HBV-infected Patients and Its Clinical Significance / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the relationship between HBV DNA and serum IL-18 level in patients with hepatitis B virus. METHODS They were divided by MEIA method into 3 groups. group AHBsAg+, HBeAg+ and HBcAb +(A); group BHBsAg+, HBeAb+ and HBcAb+(B); and group CHBsAb+(as normal controls ). Serum IL-18 level was determined by ELISA method in hepatitis patients and normal controls and HBV DNA was determined continuously . RESULTS Concentration of serum IL-18 in patients with different type of viral hepatitis was significantly higher than those in healthy volunteers(P