Effects of polyphends of Vitis amurensis Rupr on stability of RBC-membrane structure in rats / 吉林大学学报(医学版)

ABSTRACT

Objective To study the anti-ageing and antioxidation of polyphends of vitis amurensis Rupr(PVAR).Methods Forty senile male Wistar rats (20 months) were divided into 4 goups according rats′ weightssenile negtive control group(A), fed with basic forage;two senile PVAR groups(B and C),fed with basic forage inchuding 200 and 400 mg?kg~ -1 ?d~ -1 PVAR;senile positive control(D), fed with basic forage inchuding 200 mg?kg~ -1 ?d~ -1 melissic powder.After fed continuously for 8 weeks,the MDA contents in RBC-membrane, plasma and liver,sulfhydryl content in RBC-membrane, sialic acid content,activity of Na~+-K~+-ATPasc, fluidity of RBC-membrane,and activity of plasma GSH-Px in rats were detected.Results Compared with group A,the contents of MDA in groups B,C,and D decreased significantly(P