Study on quality standards for Haishengsu injection / 中国海洋药物

ABSTRACT

Objective To establish the quality control methods and HPLC fingerprint for Haishengsu Injection,a kind of extractions from Tegillarca granosa.Methods Biuret reaction and ninhydrin reaction were used for identification of the Haishengsu Injection.Nitrogen content in the Haishengsu Injection was determined by N_(2) method(semi-trace method).HPLC was used to establish the fingerprint.Other indices of the product were determined.Results The results of the biuret reaction and ninhydrin reaction were positive.Nitrogen content in the Haishengsu Injection was not less than 0.4mg?mL~(-1).And different batches of the Haishengsu Injection have the same dactylogram diagrams.Conclusion We have established rapid,convenient and accurate methods which is suitable and can be used for quality control of the Haishengsu Injection.