Expression of monocyte chemoattractant protein-1 in lupus nephritis and its clinical significance / 临床检验杂志
Chinese Journal of Clinical Laboratory Science
; (12)2006.
Article
em Zh
| WPRIM
| ID: wpr-587717
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the changes of monocyte chemoattractant protein-1(MCP-1)in serum and urine of lupus nephritis(LN)patients in active phase and remission phase.Methods The levels of MCP-1 in serum and urine of 58 LN patients(27 of active phase and 31 of remission phase)were measured by ELISA.The correlation between the levels of MCP-1 in variant phase of LN and other relevant factors were analyzed.Results The MCP-1 levels in sera of both active phase and remission phase of LN patients were markedly higher than those in controls(548.5?347.2 ng/L and 469.1?298.4 ng/L vs 273.3?146.7 ng/L,P0.05).Conclusion The MCP-1 levels in urine of LN patients is more suitable to evaluate the activity of disease as a sensitive marker.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Clinical Laboratory Science
Ano de publicação:
2006
Tipo de documento:
Article