Nuclear factor kappa B and diabetic retinopathy / 医学研究生学报
Journal of Medical Postgraduates
; (12)2004.
Article
em Zh
| WPRIM
| ID: wpr-588212
Biblioteca responsável:
WPRO
ABSTRACT
Diabetic retinopathy is a highly specific vascular complication of both type 1 and type 2 diabetes.NF-?B can be triggered by oxidative stress and controls several programs of gene expression,the majority of which participate in the host inflammation and immune response.Evidence has accumulated that NF-?B is involved in the development of diabetic retinopathy.NF-?B activation induced by diabetes is associated with the apoptosis found in the pericyte,leukocyte-endothelial interaction,capillary basement membrane thickening,neovascularization and formation of epiretinal membranes.Inhibition of(NF-?B) activation has been suggested as a treatment strategy in diabetic retinopathy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Medical Postgraduates
Ano de publicação:
2004
Tipo de documento:
Article