Quorum Sensing Negatively Controls Type Ⅲ Secretion Expression in Aeromonas hydrophila AH-1 / 生物化学与生物物理进展

ABSTRACT

A systematic analysis of the typeⅢ secretion genes of Aeromonas hydrophila strain AH-1 by constructing ahyR and ahyI mutant revealed that they are under quorum-sensing control. This observation was supported by the down-regulation of the TTSS genes in the presence of lacZ-TTSS gene promoter and the corresponding advanced secretion of AexT in ahyI mutant.