Distribution of Pathogens and Drug Resistance in Liver Cirrhosis Patients Combined with Spontaneous Bacterial Peritonitis / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To evaluate the distribution and drug resistance of pathogens in patients of liver cirrhosis combined with spontaneous bacterial peritonitis(SBP),and provide the credible evidence with the clinic diagnosis and the treatment of SBP.METHODS Totally 113 cases of hospitalized cirrhotic patients with SBP were admitted to our hospital between Mar,2000 and Dec,2005.Ascitic fluids of all cases were cultured.The total 114 strains of pathogens were identified and the drug resistance was analyzed.RESULTS Escherichia coli among the pathogens infected the ascitic fluids rated the top(39.5%),the next were Klebsiella pneumoniae,Enterobacter cloacae and Acinetobacter baumannii.The drug resistance of E.coli to imipenem was the lowest,about 2.2%.CONCLUSIONS The diagnosis of SBP with cirrhosis mainly depended on both of ascites results and clinical symptoms.The clinic should reasonably choose the antibiotics according to the test results of the pathogens sensitivity to drugs.