In vitro and in vivo anti-tumor effects of dendritic cell vaccines sensitized by NCI-H460 lung cancer cell line / 中国肿瘤生物治疗杂志

ABSTRACT

DC group.IL-12 secretion in IL-18/fusion group was higher than that in the fusion group,and IL-12 in the pulsed DC group was higher than that in the DC group.The in vitro killing rates of the 4 groups were 79.73%,50.68%,35.81% and 4.05%,respectively.Tumor forming time in IL-18/fusion group([12.82?2.85]d) was longer than those in the pulsed DC group([8.52?1.97]d,P