Biomechanical characteristics after artificial intervertebral disc implantation / 中国组织工程研究

ABSTRACT

AIM: To analyze biomechanical characteristics after artificial intervertebral disc implantation. METHODS: A computer-based online search of Pubmed database and Chinese Journal Full-text Database was undertaken to identify articles about artificial lumbar intervertebral disc application. In addition, the articles published in authoritative journal in recent 5 years were selected firstly. Repetitive studies or Meta analysis were excluded. The references of each article were looked up, and summarized. RESULTS: ①Artificial intervertebral disc can rebuild and retain normal physiologic activities of spine. How to design the rotation center of each lumbar moving segment to make it move with flexion, extension, lateral flexion and rotation, and axial rotation along with lumbar lateral flexion. ②Although the material and design are different, current used several prostheses have common movement mechanism, i.e. ball-joint, similar to Fernst joint metal ball, which is not found in normal intervertebral disc. ③With the development of intervertebral disc replacement, it has become an novel technique to treat intervertebral lumbodorsal pain. Although many prosthesis is under exploration, some reports and short-follow up results have suggested intervertebral disc replacement retains spine activity, significantly relieves pain in short period of time, and improves life of quality. But the long-term follow up is little. CONCLUSION: It is documented that artificial intervertebral disc can remain enough height of intervertebral space and lumbar motion function. The short-term clinical outcomes are fair, but long-term effect still needs further clinical experiments and long-term follow up.