Inhibitory effect of valsartan on intimal hyperplasia in rabbit autogenous grafted veins / 中国组织工程研究

ABSTRACT

0.05). In the control group, the intima of grafted veins were thickened evidently with proliferated vascular smooth muscle cells (VSMCs) and the media thickness were slight. Compared with the control group, the intima was slightly thickened in the treatment group, but there were significant reductions in proliferated VSMCs. Additionally, the media thickness was unobvious in treatment group. Compared with the control group, the thickness and area of neointima and the expression of PCNA in the treatment group were significantly lower than those in the control group (P