Quantitative microradiographic analysis of remineralization of enamel lesions promoted by casein phosphopeptide amorphous calcium phosphate and fluoride / 吉林大学学报(医学版)

ABSTRACT

Objective To evaluate the remineralization effect of casein phosphopeptide amorphous calcium phosphate(CPP-ACP) and fluoride complex on artificial enamel subsurface white spot lesions in vitro in order to provide a new method to treat the postorthodontic enamel demineralization.Methods Extracted premolar teeth for orthodontic reason were immersed into lactic acid gel to prepare artificial white spot lesions.Then the specimens were randomly assigned to seven groups5.0%CPP-ACFP group,1.0% CPP-ACP group,0.1% CPP-ACPgroup,calcium phosphate saturated solution group,calcium phosphate saturated solution plus fluorid group,deionized water group.Lesion depths and mineral loss were quantitatively determined by microradiography in various groups.Results The lesion depths and mineral loss after remineralization in each group were significantly reduced(P0.05),but the lesion depths and mineral loss in these three groups were significantly lower than those in deionized water group(P