Transcatheter closure of congenital heart defects in 16 cases using domestic-made occluders / 中国组织工程研究

ABSTRACT

Sixteen patients with congenital heart disease,4 males,12 females,aged 5-52 years,admitted to Department of Cardiology,Tianchang People's Hospital from October 2007 to November 2008 were retrospectively analyzed.All patients were diagnosed by echocardiography as 4 with congenital patent ductus arteriosus(PDA),6 atrial septal defect(ASD) and 6 ventricular septal defect(VSD).The diameter limitation of PDA,ASD and VSD are 5-17 mm,20-32 mm,and 4-10 mm,respectively.All patients received transcatheter-closure therapy by domestic-made occluders,and diameters of PDA,ASD and VSD were monitored using angiography and echocardiography.The treatment effect was evaluated by echocardiography 72 hours after procedure.The closure rate was 100%,without severe complications.No residual shunt was observed 72 hours after procedure.Four patients developed fever,including 2 acute respiratory infection and 2 pulmonary infection with balanced anesthesia;1 patient with ASD and 2 with VSDs developed arrhythmia.Results suggest that transcatheter closure of congenital heart defects(PDA,ASD and VSD) using domestic-made occluders is safe and effective according to strict indications.