Diagnostic value of proton magnetic resonance spectroscopy in patients with minimal hepatic encephalopathy / 临床神经病学杂志

ABSTRACT

Objective To study the diagnostic value of proton magnetic resonance spectroscopy(MRS) in patients with minimal hepatic encephalopathy(MHE).Methods MRS of cingulated cortex and frontal lobe were acquired using point resolved echo spin spectroscopy(PRESS) sequences in 26 patients with MHE.Peak area of each metabolite,including NAA,Cr,Cho,mI,Glx and their ratios to Cr were computed,respectively.Then the results were compared with normal control group.Results Compared with the normal control group,MHE group showed significant decreased Cho/Cr,mI/Cr(P0.05).Conclusions The patients with MHE show that Cho and mI significantly decrease and Glx significantly elevate in cingulate cortex and frontal lobe on MRS.Diagnostic value of MRS is significant to MHE.