Distribution of Pathogens and Their Antibiotic Resistance / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To understand the clinical hospital pathogens and the distribution of spectrum resistance trends in the past four years to control nosocomial infection and provide reasonable basis for therapy.METHODS From 2004 to 2007 the pathogens were isolated,identified and taken drug sensitivity tests.RESULTS During the 4 years,3176 isolates were collected.Gram positive(G+) cocci accounted fro 44.23%,?-hemolytic streptococcus,Staphylococcus aureus,Streptococcus pneumonial,coagulase-negative Staphylococcus and Enterococcus faecalis were the main pathogens.Gram-negative(G-) bacilli accounted for 40.65%,in order were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa and Moraxella catarrhalis.Fungi(Candida albicans) accounted for 16.30%.G+ cocci and G-bacilli showed different levels of resistance.Most of G+ cocci were sensitive to vancomycin.The G-bacilli were sensitive to imipenem.CONCLUSIONS Strengthening the monitoring of the clinical pathogenic bacteria and drug resistance is of great significance to control nosocomial infection and treatment.