Distribution of Pathogens of Nosocomial Infection in Neonate Ward and Analysis of Their Drug Resistance / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To study the distribution of pathogens of nosocomial infection in neonate ward and analysis of their drug resistance. METHODS Blood was cultured in BacT/Alert3D of Bio-Merieux of France,The clinical isolates were identified by VITEK-60 of Bio-Merieux of France. Using K-B agar diffusion method and confirmed test,the drug resistance of extended spectrum ?-lactamases (ESBLs) producing Klebsiella pneumoniae and Escherichia coli were detected. RESULTS The incidence of coagulase-negative staphylococcus was 76.5% in blood culture,K. pneumoniae was mostly isolated from sputum and throat swab (80.0%),The incidence of ESBLs was 57.1% in E. coli and 87.2% in K. pneumoniae. CONCLUSIONS We must control nosocomial infection,doctors should choose proper antibiotic and according to analysis of their drug resistance.