Apoptotic induction of Aspisol on melanoma A375 cells / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 425-426,后插四, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-595303
ABSTRACT
Objective To study the apoptotic induction of Aspisol on melanoma A375 cells.Methods The growth inhibition effect of Aspisol on A375 cells was evaluated by MTY assay.Morphological assay was observed by inverted microscope.Early apoptofic rate in A375 cells Was anyzed by flow cytometry.Results The results of MTT assay demonstrated that the growth of A375 cells was inhibited by Aspisol in a time-and concentration-dependence (P<0.01).FCM analysis showed that Aspisol could markedly induce apeptosis;the early apoptotie rate of A375 cells exposed to different concentrations of Aspisol for 24 h were significant differences(P<0.05)compared with control group.Conclusion Aspisol could inhibit proliferation and induce apoptosis of A375 cells.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS