Bacterial Infection and Drug Susceptibility Analysis of 91 Victims Wounded in Wenchuan Earthquake / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the bacterial infection and drug susceptibility of 91 victims wounded in Wenchuan earthquake from Sichuan and provide the laboratory evidences for sequential treatment.METHODS The specimens such as sputum,wound secretion,urine,blood,stool and necrotic tissue from the wounded were cultured on different kinds of culture medium under the aerobic or the anaerobic condition.The isolated bacteria were identified by VITEK GN analyzer or GP cards and API 20C analyzer for fungus.The drug susceptibility tests were carried out by the K-B method.RESULTS 91 wounded(58.7%) were infected,most of them were more than 60 years old.Respiratory tract(49.5%),wound(30.0%) and urinary tract(6.6%) were the main infectious sites.Among 91 strains of isolated bacteria,56 strains were G-bacilli(61.5%),20 were G+ bacteria(22.0%) and 12 strains were fungi(13.2%).The most common species among them were Escherichia coli(13.2%),fungi(13.2%),Acinetobacter(11.0%),Burkholderia cepacia(11.0%),Enterococcus(9.9%) and Staphylococcus aureus(9.9%).Drug susceptibility results showed that except the Pseudomonas aeruginosa and B.cepacia,the most G-bacilli were sensitive to imipenem,but resistant to the first and second-generation cephalosporins.The most G+ cocci were sensitive to VAN,LNZ and QDA antibiotics,and the fungus were sensitive to antibiotics used commonly in clinical treatment.CONCLUSIONS The pathogenic culture and the drug susceptibility analysis of the victims wounded in Wenchuan earthquake are inportant to guide the anti-infectious treatment.