Repair of Nasal Septal Perforation with Three-layer Graft under Nasal Endoscope / 中国微创外科杂志

ABSTRACT

Objective To explore the efficacy of nasal septal perferation with three layers of grafts under nasal endoscope. Methods From June 2002 to June 2007,15 cases of nasal septal perforation were repaired by three laryers of grafts using the perpendicular plate of the ethmoid bone or quadrangular cartilage covered by fascia lata of the thigh. The course of the disease ranged from 6 months to 5 years (mean,1.8 years) and the diameter of the perforation ranged from 0.8 to 1.6 cm (mean,1.2 cm). A 1-2 mm new surface was made along the margin of the perforation,and then the nasal septum was separated by means of submucos correction. Afterwards,a perpendicular plate of the ethmoid bone or quadrangular cartilage covered by fascia lata of the thigh was used to form a three-layer graft for seal of the perforation. Then,the nasal cavities were filled with expansive sponge,which was expanded by injecting lyophilized recombinant bovine basic fibroblast growth factor for external use. Results The surface of the graft was completely covered by nasal mucosa in 6 to 12 weeks after the surgery.Afterwords,the patients were followed up for 6 to 12 months (mean,8.2 months),during which no recurrence occurred. Conclusions It is effective to repair nasal septal perforation with three-layer graft under nasal endoscope.