Recent advances in the research on pancreatic cancer stem cell / 基础医学与临床

ABSTRACT

Only a specifc subset of cancer cells in each tumor with characteristics of self-renewal and multilineage differentiation is responsible for tumor initiation,propagation and chemoresistance,they are termed as cancer initiating cells or cancer stem cells (CSCs). This review summarizes the latest advances about the isolation and identification of pancreatic cancer stem cells and and its relationship with invasion and metastasis,chemotherapy resistance.