Relation of Immun Function State with Patient of Invasive Fungal Infect that Peripheral Blood Appear Plasmocyte / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To know the immunate function state when patients with invasive fungal infection appearing peripheral blood plasmacyte.METHODS Twenty cases of invasive fungal,bacterial infection and normal concentrate blood smear if apper plasmacyte and quantity;adopt flow cytometer technology,nephelometry were used to detect lymphocyte subpopulation,immunoglobulin level.RESULTS Concentrate blood smear find plasmacyte in 15 case invasive fungal infect patient,commonly bacterial infect only 1 case.nomal had not find.invasive fungal infection patien lymphocyte subpopulation CD3+(50.2?6.1)%,CD4+(23.6?3.5)%,lower than normal CD3+(66.8?8.0)%,CD4+(35.2?5.1)%.But CD8+(33.9?4.5)%,CD19+(34.2?7.0)% there were hinger than normal CD8+(26.5?6.5)%,CD19+(12.0?4.9)%,CD16/56+ parting(18.8?5.1%,18.2?7.0%).There ware no marked difference in two group of invasive fungal infect patients and normal immunoglobulin level partingIgG 8.35,7.72 g/L,IgA 1.59,0.99 g/L,IgM 1.20,1.07 g/L.CONCLUSIONS Invasive fungal infect patients when concentrate blood smear find plasmacyte,are found with low immune and blood serum immunoglobulin level with NK cell quantity no obvious change;but CD19+ lymphocyte quantity increase.