The correlation between hepatitis B virus gene mutation at site 1896 in precore region and genotypes as well as liver function / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 680-681,684, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-597555
ABSTRACT
Objective To analyze the relationship between hepatitis B virus gene mutation at site 1896 in precore region and genotypes as well as liver function parameters. Methods The fluorescent quantitative PCR and sequencing method were applied to measuring the relevant indicators in 50 patients with chronic hepatitis B. Results There was significant difference in ALT level between hepatitis B patients with site 1896 mutation and ones with wild-type; and HBV mutation at site 1896 in precore region was unrelated to the genotypes. Conclusion HBV mutation at site 1896 in precore region may be associated with continous viral invasion invasion into hepatocytes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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