SYNTHESIS OF SARMENTOSIN / 药学学报
Acta Pharmaceutica Sinica
;
(12): 0-1999.
Artigo
em Chinês
| WPRIM
| ID: wpr-597762
ABSTRACT
AIM:
The synthesis of sarmentosin.METHODS:
Condensation of butane-1,2,4-triol-1,2-acetonide(3) with α-D-glucopyranosyl bromide tetraacetate in the presence of Ag2O and molecular sieves gave the desired β-glucoside 4,which was transformed into sarmentosin via a reaction sequence of 7 steps.RESULTS:
The overall yield is 5.8%.CONCLUSION:
The first synthesis of sarmentosin(1),a potent natural GPT lowering agent,was achieved.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
1999
Tipo de documento:
Artigo
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