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Diagnostic value of head-up tilt test with sublingual isosorbide dinitrate in patients with vasovagal syncope / 心血管康复医学杂志
Chinese Journal of cardiovascular Rehabilitation Medicine ; (6): 83-87, 2013.
Artigo em Inglês | WPRIM | ID: wpr-598149
ABSTRACT

Objective:

To explore the diagnostic value of head-up tilt test with sublingual isosorbide dinitrate (HUTSI)in patients with vasovagal syncope (VVS).

Methods:

A total of fifty-two consecutive patients with clinically vasovagal syncope (VVS group) and thirty-eight control subjects without prior experience of syncope (normal control group) were evaluated by baseline head-up tilt table test (BHUT) , then the BHUT negative subjects underwent HUTSI test. .

Results:

(1) Positive BHUT test rate of VVS group and normal control group were 25% (13/52) and 0 respectively; from supine to HUT positive, there were significant decrease in heart rate [(73.1±8.5) times/min vs. (56.2±11.2) times/min] and mean arterial pressure [MAP, (81.2± 10.8) mmHg vs. (50.2±10.4) mmHg,P<0.05 both] in BHUT positive subjects. There were 21 HUTSI positive cases(53.9%)among the other 39 VVS patients, and two cases(5.3%)among the 38 subjects of normal control group. From supine to HUTSI positive, there were significant decrease in heart rate [(65.2±7.5) times/min vs. (52.9±10.5) times/min] and MAP [(78.3±10.7) mmHg vs. (48.8±11.2) mmHg, P<0.05 both] in HUTSI positive subjects. Duration from tilt started to positive reaction occurred in HUTSI positive group was significantly shorter than that of BHUT positive group [(10.8±9.3) min vs. (21.1±11.5) min,P<0.05]. All subjects can tolerate the test and only two cases in VVS group and one case in normal control group occurred headache and face red.

Conclusion:

Head-up tilt test with sublingual isosorbide dinitrate is a practical and easy-to- perform method with high sensitivity, specificity and few side effects for diagnosis of vasovagal syncope.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico Idioma: Inglês Revista: Chinese Journal of cardiovascular Rehabilitation Medicine Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo diagnóstico Idioma: Inglês Revista: Chinese Journal of cardiovascular Rehabilitation Medicine Ano de publicação: 2013 Tipo de documento: Artigo