Study on the inclusion actions of diclofenac sodium and β-cyclodextinr in aqueous solution / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 165-1999.
Artigo
em Chinês
| WPRIM
| ID: wpr-598326
ABSTRACT
OBJECTIVE:Probe into the feasibility of preparation of diclofenac sodium with β-cyclodextrins in 1∶1 and 2∶1 inclusion compounds ,and find out the affection in solubility of diclofenac sodium. METHODS:
The 1∶1 and 2∶1 melusion compounds were prepared by liquid-phase an alysis the content and determination them solubility.RESULT:
The 1 ∶1 and 2∶1 inclusion compounds were prepared by different ratio of reactants and etermined them mp were 299~300.5℃ and 302~303℃ respectively. CONCLUSION:Of us is that solubilits of the 1∶1 and 2∶1 inclusion compounds increase 0.65 and 1 times respetively comparing with declofenac sodium.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
1999
Tipo de documento:
Artigo
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