New evidences of α7nAChR participating in 100 Hz EA regulating NK cells activity / 重庆医学
Chongqing Medicine
; (36): 582-583,586, 2014.
Article
em Zh
| WPRIM
| ID: wpr-598811
Biblioteca responsável:
WPRO
ABSTRACT
Objective On the basis of previous experiments ,we try further to seek the new evidences of α7nAChR participating in 100 Hz electroacupuncture (EA ) regulating natural killer (NK ) cells activity .Methods α7nAChR antibody and the specificα7nAChR antagonist α-bungarotoxin (α-Bgt) were used to study the effect of α7nAChR on NK cell activity in 100 Hz EA mice .Re-sults Compared with 100 Hz EA group ,100 Hz EA plus α7nAChR-Ab group showed a significant enhanced in NK cell activity (P<0 .05) .100 Hz EA treated with 1 .5 or 3 .0 μg α-Bgt groups had higher NK cell activity than 100 Hz EA group(P<0 .01) . Conclusion α7nAChR is involved in 100 Hz EA modulation for immune function ,which provide the theoretical and practical basis for further clarifying and expanding the clinical application of EA .
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chongqing Medicine
Ano de publicação:
2014
Tipo de documento:
Article