Anti-inflammatory mechanism of alpha 7 nicotinic acetylcholine receptors / 国际儿科学杂志

ABSTRACT

Alpha nicotinic acetylcholine receptors(α7nAChR) is a classic neurotransmitter receptor. Re-cent studies have found α7nAChR plays a key role in the cholinergic anti-inflammatory pathway. In this paper, biology characteristics ofα7nAChR molecular,the relationship with cholinergic anti-inflammatory pathway,anti-inflammatory effects of intracellular mechanisms,clinical application are reviewed.