The clinical significance of procalcitonin and hypersensitive c-reactive protein test in ;early newborn infection / 中国医学装备

ABSTRACT

Objective:To discuss the clinical significance of procalcitonin(PCT) and hypersensitive c-reactive protein(hs-CRP) test in early newborn infection. Methods:Sixty cases of our hospital treatment confirmed infection early newborn children were selected from June 2007 to July 2007,according to the condition was divided into severe infection group and local infection group, at the same time, 30 cases of our new pediatric infection in early neonatal were chosen as control group, to collect the moderate amount of peripheral blood of three groups before and after the treatment, detected and analyzed the levels of PCT and hs-CRP in the serum, Used Pearson correlation analysis to analysis the correlation of PCT and hs-CRP in the serum. Results: Severe infection group serum PCT, hs CRP levels and positive rate higher than that of local infection group, local infection group of PCT, hs CRP levels and positive rate is higher than the control group, the difference was statistically significant; Infection group before treated with serum PCT and hs-CRP levels and positive rate were higher than after treated(x2=7.248, x2=6.934; P<0.05); Pearson correlation analysis show that, according to the results of PCT and hs-CRP were positively correlated (r=0.533, P<0.533). Conclusion:Procalcitonin and hypersensitive c-reactive protein plays an important role in the infections of early neonatal children, PCT and hs-CRP were positively correlated, it can be used as an important index of early diagnosis of early neonatal infectious diseases.