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Thalamus segmentation based on resting-state functional magnetic resonance imaging / 国际生物医学工程杂志
International Journal of Biomedical Engineering ; (6): 1-4,后插3, 2015.
Artigo em Chinês | WPRIM | ID: wpr-601625
ABSTRACT
Objective To obtain an accurate and effective method for thalamus segmentation based on resting-state functional magnetic resonance imaging (fMRI).Methods Based on the fact that resting-state fMRI technique examined spatial synchronization of spontaneous fluctuations in blood oxygen level-dependent (BOLD) signals indirectly reflect the neuronal and synaptic activity,the in-thalamus BOLD signal correlations were calculated,and then the k-means clustering algorithm was applied to obtain functional connectivity-based thalamus segmentation.Results The thalamus was divided into seven regions.Voxels within the same region were highly correlated with each other.The segmentation result was similar to that divided by functional connectivity between thalamus and the cerebral cortex.Conclusions Resting-state fMRI could provide not only the functional connectivity network between cortical and subcortical brain regions,but also the functional characteristics of thalamus.Segmentation algorithm using only internal information of thalamus shows lower computational complexity and higher processing speed than that based on the functional connectivity between thalamus and the cerebral cortex.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Biomedical Engineering Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Biomedical Engineering Ano de publicação: 2015 Tipo de documento: Artigo