Escaping mechanism from innate immunity mediated clearance by high pathogenic influenza virus during infection / 中国免疫学杂志

ABSTRACT

Severe influenza infection is usually associated with hypercytokinemia ,but the type Ⅰ Interferon remains at low lever or absence.The regulatory mechanism on or the immune escaping mechanism from type I interferon by virus remains to be deter -mined.We briefly summarized the progress in this field and raise several questions to be addressed in the future .