Comparison of the clinical effect of ornidazole and metronidazole in the treatment of trichomonal vaginitis / 中国基层医药

ABSTRACT

Objective To observe and compare the clinical efficacy of ornidazole and metronidazole in the treatment of trichomonal vaginitis.Methods We selected 64 patients with trichomonal vaginitis who were treated in our hospiatl from January 201 3 to December 201 4,and they were divided into the observation group and the control group,each group had 32 cases.The observation group was treated with ornidazole,while the control group was treated with metronidazole.The clinical efficacy,yellow leucorrhea,frequent urination,and other clinical symptoms and adverse reactions of the two groups were compared.Results The total effective rate of the ornidazole group was 96.875%,which of the metronidazole group was 81 .75%.The ornidazole group was significantly better than the met-ronidazole group,and there was significant difference (χ2 =6.869,P 0.05).After treatment,the clinical symptoms incindenceyellow leucorrhea,frequent urination,etc of the ornidazole group was significantly lower than those of the metronidazole group,and there were significant differences (χ2 =6.594,8.256,6.783,6.469,all P <0.05 ).The incidence of adverse reaction of the ornidazole group was significantly lower than that of the metronidazole group,and there was significant difference (χ2 =8.325,P <0.05).Conclusion The clinical efficacy of ornidazole for the treament of trichomonas vaginitis was significantly better than metronidazole,and the clinical symptoms improved more significantly, it has higher safety and worthy of clinical application.