Intervention Effects of Pollen Typhae Total Flavone on INS-1 PancreaticβCells Damage Induced by Palmitic Acid / 广州中医药大学学报
Journal of Guangzhou University of Traditional Chinese Medicine
;
(6): 899-902,913, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-603506
ABSTRACT
Objective To investigate the effects of Pollen Typhae total flavone (PTF) on INS-1 pancreaticβcell damage induced by palmitic acid ( PA) . Methods INS-1 pancreatic β cells were given long-term induction with PA to establish the impaired cell model, and then were intervened with PTF. Cell viability was determined by tetrazolium salt ( XTT) colorimetry. Results PA impaired the viabilities of INS-1 pancreatic β cells in concentration- and time-dependent manner, and PTF improved the impairment of INS-1 pancreatic β cells induced by PA in concentration -dependent manner. Moreover, PTF showed better improvement on the impairment when the INS-1 pancreatic β cells were impaired more seriously by PA. Conclusion PTF has effects on ameliorating the impairment of INS-1 pancreaticβcells induced by PA for long time.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Guangzhou University of Traditional Chinese Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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