Research progress on association of LRP6 gene polymorphism and metabolic syndrome / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 603-606,607, 2016.
Article
em Zh
| WPRIM
| ID: wpr-604050
Biblioteca responsável:
WPRO
ABSTRACT
Metabolic syndrome is the fundamental factor in the pathogenesis of a variety of diseases, and it has not yet been fully understood due to its complicated mechanism. Multiple re-searches have implicated that Wnt/β-catenin signaling pathway may have a significant effect on the formation and development of metabolic syndrome. LRP6 is an important co-receptor of Wnt/β-catenin signaling pathway ,and there are some researches im-plicating the correlation between LRP6 and metabolic syndrome. The in-depth research on the gene polymorphism and its modula-tion mechanism can provide new ideas and directions for meta-bolic syndrome therapy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2016
Tipo de documento:
Article