Effects of Ginkgo biloba Extract on Proliferation and Apoptosis of Gastric Cancer Cell Line SGC7901 / 中国药房
China Pharmacy
;
(12): 3510-3511,3512, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-605193
ABSTRACT
OBJECTIVE:
To investigate the effects of Ginkgo biloba extract (GBE) on proliferation and apoptosis of gastric cancer cell line SGC7901.METHODS:
After the cells were cultured in 0,5,10,20,50,100 and 200 μg/ml GBE for 48 h,cell viability was determined by MTT method and inhibition rate was calculated. After the cells were cultured in 0,10,50 and 200μg/ml GBE for 48 h,flow cytometry was used to detect cell cycle distribution and the apoptosis rate.RESULTS:
Following 48 h culture of cells in 5,10,20,50,100 and 200μg/ml GBE,the growth of cells were obviously inhibited in a dose-dependent man-ner. After 48 h culture of cells in 10,50 and 200 μg/ml GBE,the apoptosis rate was increased.CONCLUSIONS:
GBE can inhibi-tion the proliferation of SGC7901,and induces it apoptosis,the former dominated.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2015
Tipo de documento:
Artigo
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